Cohesin Loss Eliminates All Loop Domains

Cohesin Loss Eliminates All Loop Domains

The human genome folds to create thousands of intervals, called "contact domains," that exhibit enhanced contact frequency within themselves. "Loop domains" form because of tethering between two loci-almost always bound by CTCF and cohesin-lying on the same chromosome. "Comp...

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Main Authors: Rao, Suhas S.P (Author), Huang, Su-Chen (Author), Glenn St Hilaire, Brian (Author), Engreitz, Jesse M. (Author), Perez, Elizabeth M. (Author), Kieffer-Kwon (Author), Sanborn, Adrian L. (Author), Johnstone, Sarah E. (Author), Bascom, Gavin D. (Author), Bochkov, Ivan D. (Author), Huang, Xingfan (Author), Shamim, Muhammad S. (Author), Shin, Jaeweon (Author), Turner, Douglass (Author), Ye, Ziyi (Author), Omer, Arina D. (Author), Robinson, James T. (Author), Schlick, Tamar (Author), Bernstein, Bradley E. (Author), Casellas, Rafael (Author), Aiden, Erez Lieberman (Author), Lander, Eric Steven (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Elsevier, 2018-11-07T16:58:58Z.
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