Dynamic changes in ORC localization and replication fork progression during tissue differentiation

Background Genomic regions repressed for DNA replication, resulting in either delayed replication in S phase or underreplication in polyploid cells, are thought to be controlled by inhibition of replication origin activation. Studies in Drosophila polytene cells, however, raised the possibility that...

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Bibliographic Details
Main Authors: Kashevsky, Helena (Author), Von Stetina, Jessica R. (Author), Bell, George W. (Author), Hua, Brian (Contributor), Orr-Weaver, Terry (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: BioMed Central, 2018-08-28T14:52:00Z.
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