Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes

Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes

Stem-cell-based therapies can potentially reverse organ dysfunction and diseases, but the removal of impaired tissue and activation of a program leading to organ regeneration pose major challenges. In mice, a 4-day fasting mimicking diet (FMD) induces a stepwise expression of Sox17 and Pdx-1, follow...

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Bibliographic Details
Main Authors: Villani, Valentina (Author), Buono, Roberta (Author), Wei, Min (Author), Kumar, Sanjeev (Author), Cohen, Pinchas (Author), Sneddon, Julie B. (Author), Perin, Laura (Author), Longo, Valter D. (Author), Cheng, Chia-Wei (Contributor), Yilmaz, Omer (Contributor)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2018-07-23T18:50:49Z.
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