Origin and Functional Evolution of the Cdc48/p97/VCP AAA+ Protein Unfolding and Remodeling Machine
The AAA + Cdc48 ATPase (alias p97 or VCP) is a key player in multiple ubiquitin-dependent cell signaling, degradation, and quality control pathways. Central to these broad biological functions is the ability of Cdc48 to interact with a large number of adaptor proteins and to remodel macromolecular p...
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier,
2018-07-09T14:39:42Z.
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| Subjects: | |
| Online Access: | Get fulltext |