Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
Checkpoint blockade immunotherapies can be extraordinarily effective, but might benefit only the minority of patients whose tumors are pre-infiltrated by T cells. Here, using lung adenocarcinoma mouse models, including genetic models, we show that autochthonous tumors that lacked T cell infiltration...
Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Elsevier BV,
2018-06-22T15:39:51Z.
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Subjects: | |
Online Access: | Get fulltext |