The aneuploidy paradox: costs and benefits of an incorrect karyotype
Aneuploidy has a paradoxical effect on cell proliferation. In all normal cells analyzed to date, aneuploidy has been found to decrease the rate of cell proliferation. Yet, aneuploidy is also a hallmark of cancer, a disease of enhanced proliferative capacity, and aneuploid cells are frequently recove...
Main Authors: | , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2018-06-05T18:31:04Z.
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Subjects: | |
Online Access: | Get fulltext |