Human osteochondritis dissecans fragment-derived chondrocyte characteristics ex vivo, after monolayer expansion-induced de-differentiation, and after re-differentiation in alginate bead culture

Human osteochondritis dissecans fragment-derived chondrocyte characteristics ex vivo, after monolayer expansion-induced de-differentiation, and after re-differentiation in alginate bead culture

Background Autologous chondrocyte implantation (ACI) is a therapy for articular cartilage and osteochondral lesions that relies on notch- or trochlea-derived primary chondrocytes. An alternative cell source for ACI could be osteochondritis dissecans (OCD) fragment-derived chondrocytes. Assessing the...

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Bibliographic Details
Main Authors: Aurich, Matthias (Author), Gras, Florian (Author), Hofmann, Gunther O. (Author), Rolauffs, Bernd G (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering (Contributor)
Format: Article
Language:English
Published: BioMed Central, 2018-05-30T18:12:54Z.
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