Structured States of Disordered Proteins from Genomic Sequences

Structured States of Disordered Proteins from Genomic Sequences

Protein flexibility ranges from simple hinge movements to functional disorder. Around half of all human proteins contain apparently disordered regions with little 3D or functional information, and many of these proteins are associated with disease. Building on the evolutionary couplings approach pre...

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Bibliographic Details
Main Authors: Toth-Petroczy, Agnes (Author), Ingraham, John (Author), Hopf, Thomas A. (Author), Sander, Chris (Author), Marks, Debora S. (Author), Palmedo, Peter Franklin (Contributor), Berger Leighton, Bonnie (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Elsevier, 2018-05-17T17:03:23Z.
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