Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and

Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and

Vaccines have had broad medical impact, but existing vaccine technologies and production methods are limited in their ability to respond rapidly to evolving and emerging pathogens, or sudden outbreaks. Here, we develop a rapid-response, fully synthetic, singledose, adjuvant-free dendrimer nanopartic...

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Bibliographic Details
Main Authors: Chahal, Jasdave S. (Author), Cooper, Christopher L. (Author), McPartlan, Justine S. (Author), Tilley, Lucas D. (Author), Sidik, Saima M. (Author), Lourido, Sebastian (Author), Bavari, Sina (Author), Ploegh, Hidde L. (Author), Khan, Omar Fizal (Contributor), Tsosie, Jonathan (Contributor), Langer, Robert S (Contributor), Anderson, Daniel Griffith (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2018-04-13T19:38:07Z.
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