Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

B cells constitute an essential line of defense from pathogenic infections through the generation of class-switched antibody-secreting cells (ASCs) in germinal centers. Although this process is known to be regulated by follicular helper T (TfH) cells, the mechanism by which B cells initially seed ge...

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Main Authors: Gaya, Mauro (Author), Barral, Patricia (Author), Burbage, Marianne (Author), Aggarwal, Shweta (Author), Montaner, Beatriz (Author), Warren Navia, Andrew (Author), Aid, Malika (Author), Tsui, Carlson (Author), Maldonado, Paula (Author), Nair, Usha (Author), Ghneim, Khader (Author), Fallon, Padraic G. (Author), Sekaly, Rafick-Pierre (Author), Barouch, Dan H. (Author), Bruckbauer, Andreas (Author), Strid, Jessica (Author), Batista, Facundo D. (Author), Shalek, Alexander K (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor)
Format: Article
Language:English
Published: Elsevier, 2018-02-09T16:19:48Z.
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