Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens

Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Small molecule screens are widely used to prioritize pharmaceuti...

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Main Authors: Beeharry, Neil (Author), Fink, Lauren (Author), Bhattacharjee, Vikram (Author), Huang, Shao-shan Carol (Author), Zhou, Yan (Author), Yen, Tim (Author), Ursu, Oana (Contributor), Gosline, Sara Calafell (Contributor), Fraenkel, Ernest (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2018-01-22T16:45:18Z.
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