Copper-catalyzed asymmetric addition of olefin-derived nucleophiles to ketones
Enantioenriched alcohols found in an array of bioactive natural products and pharmaceutical agents are often synthesized by asymmetric nucleophilic addition to carbonyls. However, this approach generally shows limited functional-group compatibility, requiring the use of preformed organometallic reag...
Main Authors: | , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS),
2018-01-10T15:40:48Z.
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Subjects: | |
Online Access: | Get fulltext |