Chromosome Compaction by Active Loop Extrusion

During cell division, chromosomes are compacted in length by more than a 100-fold. A wide range of experiments demonstrated that in their compacted state, mammalian chromosomes form arrays of closely stacked consecutive ∼100 kb loops. The mechanism underlying the active process of chromosome compact...

Full description

Bibliographic Details
Main Authors: Marko, John F (Author), Goloborodko, Anton (Contributor), Mirny, Leonid A (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-12-19T14:32:06Z.
Subjects:
Online Access:Get fulltext