Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism. The maternal genome inherited from the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the zygote. How these two epigenetically distinct...

Full description

Bibliographic Details
Main Authors: Flyamer, Ilya M. (Author), Gassler, Johanna (Author), Brandão, Hugo B. (Author), Ulianov, Sergey V. (Author), Razin, Sergey V. (Author), Tachibana-Konwalski, Kikuë (Author), Imakaev, Maksim Viktorovich (Contributor), Abdennur, Nezar Alexander (Contributor), Mirny, Leonid A (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-12-19T14:07:17Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items