Multidimensional chemical control of CRISPR-Cas9

Multidimensional chemical control of CRISPR-Cas9

Cas9-based technologies have transformed genome engineering and the interrogation of genomic functions, but methods to control such technologies across numerous dimensions-including dose, time, specificity, and mutually exclusive modulation of multiple genes-are still lacking. We conferred such mult...

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Bibliographic Details
Main Authors: Maji, Basudeb (Author), Shoulders, Matthew D (Author), Choudhary, Amit (Author), Moore, Christopher (Contributor), Zetsche, Bernd (Contributor), Volz, Sara E. (Contributor), Zhang, Feng (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), McGovern Institute for Brain Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-12-13T15:31:24Z.
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