Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip

The main advance of this study is the development of a microengineered model of human intestinal inflammation and bacterial overgrowth that permits analysis of individual contributors to the pathophysiology of intestinal diseases, such as ileus and inflammatory bowel disease, over a period of weeks...

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Bibliographic Details
Main Authors: Kim, Hyun Jung (Author), Li, Hu (Author), Collins, James J. (Contributor), Ingber, Donald E. (Author)
Other Authors: Institute for Medical Engineering and Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-09-18T15:17:52Z.
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