In-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides
A thorough investigation of the challenging Pd-catalyzed fluorination of five-membered heteroaryl bromides is presented. Crystallographic studies and density functional theory (DFT) calculations suggest that the challenging step of this transformation is C-F reductive elimination of five-membered he...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2017-07-05T15:29:51Z.
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Subjects: | |
Online Access: | Get fulltext |