Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression
The angiogenic switch, the time at which a tumor becomes vascularized, is a critical step in tumor progression. Indeed, without blood supply, tumors will fail to grow beyond 1mm[superscript 3] and are unlikely to disseminate. The extracellular matrix (ECM), a major component of the tumor microenviro...
Main Authors: | , , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2017-06-21T13:49:59Z.
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Subjects: | |
Online Access: | Get fulltext |