LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining

LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining

The Caenorhabditis elegans SUN domain protein, UNC-84, functions in nuclear migration and anchorage in the soma. We discovered a novel role for UNC-84 in DNA damage repair and meiotic recombination. Loss of UNC-84 leads to defects in the loading and disassembly of the recombinase RAD-51. Similar to...

Full description

Bibliographic Details
Main Authors: Lawrence, Katherine S. (Author), Tapley, Erin C. (Author), Cruz, Victor E. (Author), Li, Qianyan (Author), Aung, Kayla (Author), Hart, Kevin C. (Author), Starr, Daniel A. (Author), Engebrecht, JoAnne (Author), Schwartz, Thomas (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Rockefeller University Press, 2017-06-16T19:17:49Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items