Automated pipeline for rapid production and screening of HIV-specific monoclonal antibodies using pichia pastoris

Automated pipeline for rapid production and screening of HIV-specific monoclonal antibodies using pichia pastoris

Monoclonal antibodies (mAbs) that bind and neutralize human pathogens have great therapeutic potential. Advances in automated screening and liquid handling have resulted in the ability to discover antigen-specific antibodies either directly from human blood or from various combinatorial libraries (p...

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Bibliographic Details
Main Authors: Shah, Kartik A (Contributor), Clark, John J (Contributor), Goods, Brittany A. (Contributor), Politano, Timothy James (Contributor), Mozdzierz, Nicholas Joseph (Contributor), Zimnisky, Ross (Contributor), Leeson, Rachel (Contributor), Love, John C (Contributor), Love, Kerry R. (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Innovation (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2017-05-30T20:04:48Z.
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