Acid activation mechanism of the influenza A M2 proton channel
The homotetrameric influenza A M2 channel (AM2) is an acid-activated proton channel responsible for the acidification of the influenza virus interior, an important step in the viral lifecycle. Four histidine residues (His37) in the center of the channel act as a pH sensor and proton selectivity filt...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
National Academy of Sciences (U.S.),
2017-05-08T13:58:47Z.
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| Subjects: | |
| Online Access: | Get fulltext |