Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation

Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation

The effectiveness of stem cell therapies has been hampered by cell death and limited control over fate. These problems can be partially circumvented by using macroporous biomaterials that improve the survival of transplanted stem cells and provide molecular cues to direct cell phenotype. Stem cell b...

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Main Authors: Lippens, Evi (Author), Lee, Kangwon (Author), Mehta, Manav (Author), Koshy, Sandeep T (Author), Darnell, Max C (Author), Desai, Rajiv M. (Author), Madl, Christopher M (Author), Xu, Maria (Author), Zhao, Xuanhe (Author), Chaudhuri, Ovijit (Author), Verbeke, Catia (Author), Kim, Woo Seob (Author), Alim, Karen (Author), Mammoto, Akiko (Author), Ingber, Donald E (Author), Duda, Georg N (Author), Mooney, David J (Author), Huebsch, Nathaniel David (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-04-14T14:46:28Z.
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