Enzyme-Mediated Modification of Single-Domain Antibodies for Imaging Modalities with Different Characteristics

Antibodies are currently the fastest-growing class of therapeutics. Although naked antibodies have proven valuable as pharmaceutical agents, they have some limitations, such as low tissue penetration and a long circulatory half-life. They have been conjugated to toxic payloads, PEGs, or radioisotope...

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Bibliographic Details
Main Authors: Rashidian, Mohammad (Author), Wang, Lu (Author), Edens, Jerre G. (Author), Jacobsen, Johanne T. (Author), Hossain, Intekhab (Author), Wang, Qifan (Author), Victora, Gabriel D. (Author), Vasdev, Neil (Author), Liang, Steven H. (Author), Ploegh, Hidde (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2017-04-10T13:10:22Z.
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