Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans

Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans

The translation initiation factor eIF3 is a multi-subunit protein complex that coordinates the assembly of the 43S pre-initiation complex in eukaryotes. Prior studies have demonstrated that not all subunits of eIF3 are essential for the initiation of translation, suggesting that some subunits may se...

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Main Authors: Cattie, Douglas John (Contributor), Richardson, Claire Elissa (Contributor), Reddy, Kirthi C. (Contributor), Ness-Cohn, Elan M. (Contributor), Droste, Rita (Contributor), Thompson, Mary Katherine (Contributor), Gilbert, Wendy (Contributor), Kim, Dennis H. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2017-04-05T14:17:29Z.
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