Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans

The ability of phagocytes to clear pathogens is an essential attribute of the innate immune response. The role of signaling lipid molecules such as phosphoinositides is well established, but the role of membrane sphingolipids in phagocytosis is largely unknown. Using a genetic approach and small mol...

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Bibliographic Details
Main Authors: Tafesse, Fikadu G. (Author), Rashidfarrokhi, Ali (Author), Freinkman, Elizaveta (Author), Dougan, Stephanie (Author), Dougan, Michael (Author), Esteban, Alexandre (Author), Maruyama, Takeshi (Author), Strijbis, Karin (Author), Schmidt, Florian Ingo (Contributor), Ploegh, Hidde (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2017-03-07T16:53:53Z.
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