Virtual microfluidics for digital quantification and single-cell sequencing

We have developed hydrogel-based virtual microfluidics as a simple and robust alternative to complex engineered microfluidic systems for the compartmentalization of nucleic acid amplification reactions. We applied in-gel digital multiple displacement amplification (dMDA) to purified DNA templates, c...

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Bibliographic Details
Main Authors: Xu, Liyi (Contributor), Brito, Ilana Lauren (Contributor), Alm, Eric J (Contributor), Blainey, Paul C (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-02-23T18:21:59Z.
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