Effects of insulin-like growth factor-1 and dexamethasone on cytokine-challenged cartilage: relevance to post-traumatic osteoarthritis

Objective: Interleukin-1 is one of the inflammatory cytokines elevated after traumatic joint injury that plays a critical role in mediating cartilage tissue degradation, suppressing matrix biosynthesis, and inducing chondrocyte apoptosis, events associated with progression to post-traumatic osteoart...

Full description

Bibliographic Details
Main Authors: Chubinskaya, S. (Author), Schoeberl, B. (Author), Florine, E. (Author), Kopesky, P. (Author), Li, Yang (Contributor), Grodzinsky, Alan J (Contributor), Wang, Yang (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-02-02T18:33:20Z.
Subjects:
Online Access:Get fulltext