Characterisation of liver pathogenesis, human immune responses and drug testing in a humanised mouse model of HCV infection

Characterisation of liver pathogenesis, human immune responses and drug testing in a humanised mouse model of HCV infection

Objective HCV infection affects millions of people worldwide, and many patients develop chronic infection leading to liver cancers. For decades, the lack of a small animal model that can recapitulate HCV infection, its immunopathogenesis and disease progression has impeded the development of an effe...

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Main Authors: Keng, Choong Tat (Author), Sze, Ching Wooen (Author), Zheng, Dahai (Author), Zheng, Zhiqiang (Author), Yong, Kylie Su Mei (Author), Tan, Shu Qi (Author), Ong, Jessica Jie Ying (Author), Tan, Sue Yee (Author), Loh, Eva (Author), Upadya, Megha Haridas (Author), Kuick, Chik Hong (Author), Hotta, Hak (Author), Lim, Seng Gee (Author), Tan, Thiam Chye (Author), Chang, Kenneth T E (Author), Hong, Wanjin (Author), Chen, Jianzhu (Contributor), Tan, Yee-Joo (Author), Chen, Qingfeng (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: BMJ Publishing Group, 2017-01-13T16:24:50Z.
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