Longitudinal multiparameter assay of lymphocyte interactions from onset by microfluidic cell pairing and culture

Longitudinal multiparameter assay of lymphocyte interactions from onset by microfluidic cell pairing and culture

Resolving how the early signaling events initiated by cell-cell interactions are transduced into diverse functional outcomes necessitates correlated measurements at various stages. Typical approaches that rely on bulk cocultures and population-wide correlations, however, only reveal these relationsh...

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Main Authors: Servos, Mariah M. (Author), Dougan, Stephanie K. (Author), Dura, Burak (Contributor), Barry, Rachel M (Contributor), Ploegh, Hidde (Contributor), Voldman, Joel (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Microsystems Technology Laboratories (Contributor), Massachusetts Institute of Technology. Research Laboratory of Electronics (Contributor), Whitehead Institute for Biomedical Research (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2016-12-27T21:43:00Z.
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