Lack of Evidence for PKM2 Protein Kinase Activity

Lack of Evidence for PKM2 Protein Kinase Activity

The role of pyruvate kinase M2 (PKM2) in cell proliferation is controversial. A unique function of PKM2 proposed to be important for the proliferation of some cancer cells involves the direct activity of this enzyme as a protein kinase; however, a detailed biochemical characterization of this activi...

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Bibliographic Details
Main Authors: Hosios, Aaron Marc (Contributor), Fiske, Brian Prescott (Contributor), Gui, Dan Yi (Contributor), Vander Heiden, Matthew G. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-12-15T15:42:40Z.
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