Spatial reconstruction of single-cell gene expression data

Spatial localization is a key determinant of cellular fate and behavior, but methods for spatially resolved, transcriptome-wide gene expression profiling across complex tissues are lacking. RNA staining methods assay only a small number of transcripts, whereas single-cell RNA-seq, which measures glo...

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Bibliographic Details
Main Authors: Satija, Rahul (Author), Farrell, Jeffrey A (Author), Gennert, David (Author), Schier, Alexander F (Author), Regev, Aviv (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2016-12-07T20:58:05Z.
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