A three-dimensional microfluidic tumor cell migration assay to screen the effect of anti-migratory drugs and interstitial flow

Most anti-cancer drug screening assays are currently performed in two dimensions, on flat, rigid surfaces. However, there are increasing indications that three-dimensional (3D) platforms provide a more realistic setting to investigate accurate morphology, growth, and sensitivity of tumor cells to ch...

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Bibliographic Details
Main Authors: Kalchman, Johann (Author), Fujioka, Shingo (Author), Chung, Seok (Author), Kikkawa, Yamato (Author), Mitaka, Toshihiro (Author), Tanishita, Kazuo (Author), Sudo, Ryo (Author), Kamm, Roger Dale (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Springer-Verlag, 2016-10-03T18:53:14Z.
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