Quality score compression improves genotyping accuracy
To the Editor: Most next-generation sequencing (NGS) quality scores are space intensive, redundant and often misleading. In this Correspondence, we recover quality information directly from sequence data using a compression tool named Quartz, rendering such scores redundant and yielding substantiall...
Main Authors: | Yu, Yun William (Contributor), Yorukoglu, Deniz (Contributor), Peng, Jian (Contributor), Berger Leighton, Bonnie (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Mathematics (Contributor) |
Format: | Article |
Language: | English |
Published: |
Springer Nature,
2016-08-30T21:02:51Z.
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Subjects: | |
Online Access: | Get fulltext |
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