Quality score compression improves genotyping accuracy

To the Editor: Most next-generation sequencing (NGS) quality scores are space intensive, redundant and often misleading. In this Correspondence, we recover quality information directly from sequence data using a compression tool named Quartz, rendering such scores redundant and yielding substantiall...

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Bibliographic Details
Main Authors: Yu, Yun William (Contributor), Yorukoglu, Deniz (Contributor), Peng, Jian (Contributor), Berger Leighton, Bonnie (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Mathematics (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2016-08-30T21:02:51Z.
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