Stent elution rate determines drug deposition and receptor-mediated effects
Drug eluting stent designs abound and yet the dependence of efficacy on drug dose and elution duration remains unclear. We examined these issues within a mathematical framework of arterial drug distribution and receptor binding following stent elution. Model predictions that tissue content linearly...
Main Authors: | , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2016-04-28T12:35:17Z.
|
Subjects: | |
Online Access: | Get fulltext |