A transcription blocker isolated from a designed repeat protein combinatorial library by in vivo functional screen
A highly diverse DNA library coding for ankyrin seven-repeat proteins (ANK-N5C) was designed and constructed by a PCR-based combinatorial assembly strategy. A bacterial melibiose fermentation assay was adapted for in vivo functional screen. We isolated a transcription blocker that completely inhibit...
Main Authors: | , , , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2016-03-28T18:18:29Z.
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Subjects: | |
Online Access: | Get fulltext |