Elucidating MicroRNA Regulatory Networks Using Transcriptional, Post-transcriptional, and Histone Modification Measurements

Elucidating MicroRNA Regulatory Networks Using Transcriptional, Post-transcriptional, and Histone Modification Measurements

MicroRNAs (miRNAs) regulate diverse biological processes by repressing mRNAs, but their modest effects on direct targets, together with their participation in larger regulatory networks, make it challenging to delineate miRNA-mediated effects. Here, we describe an approach to characterizing miRNA-re...

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Main Authors: Gurtan, Allan M (Author), JnBaptiste, Courtney K (Author), Bosson, Andrew (Contributor), Milani, Pamela (Contributor), Matthews, Bryan J (Author), Yap, Yoon S (Author), Sharp, Phillip A. (Contributor), Fraenkel, Ernest (Contributor), Gosline, Sara Jane Calafell (Contributor), Gurtan, Allan M. (Contributor), Dalin, Simona (Author), JnBaptiste, Courtney Kenneil (Author), Matthews, Bryan (Author), Yap, Yoon Sing (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), JnBaptiste, Courtney K. (Contributor), Dalin, Simona Sara (Contributor), Matthews, Bryan J. (Contributor), Yap, Yoon S. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-03-14T17:44:54Z.
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