Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment

Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment

Long noncoding RNAs (lncRNAs) are often expressed in a development-specific manner, yet little is known about their roles in lineage commitment. Here, we identified Braveheart (Bvht), a heart-associated lncRNA in mouse. Using multiple embryonic stem cell (ESC) differentiation strategies, we show tha...

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Main Authors: Klattenhoff, Carla A (Author), Scheuermann, Johanna C (Author), Surface, Lauren E (Author), Bradley, Robert K (Author), Fields, Paul A (Author), Steinhauser, Matthew L (Author), Ding, Huiming (Contributor), Torrey, Lillian (Contributor), Haas, Simon (Contributor), Abo, Ryan (Contributor), Tabebordbar, Mohammadsharif (Contributor), Lee, Richard T (Author), Burge, Christopher B (Author), Klattenhoff, Carla A. (Contributor), Scheuermann, Johanna C. (Contributor), Bradley, Robert K. (Contributor), Fields, Paul A. (Contributor), Butty, Vincent L G (Author), Boyer, Laurie Ann (Author), Surface, Lauren Elizabeth (Author), Burge, Christopher B (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Surface, Lauren E. (Contributor), Butty, Vincent (Contributor), Burge, Christopher B. (Contributor), Boyer, Laurie (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-02-25T17:45:32Z.
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