Structure-Based Redesign of the Binding Specificity of Anti-Apoptotic Bcl-x[subscript L]
Many native proteins are multi-specific and interact with numerous partners, which can confound analysis of their functions. Protein design provides a potential route to generating synthetic variants of native proteins with more selective binding profiles. Redesigned proteins could be used as resear...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier,
2016-02-25T03:18:14Z.
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Subjects: | |
Online Access: | Get fulltext |