Helix Bundle Loops Determine Whether Histidine Kinases Autophosphorylate in cis or in trans

Bacteria frequently use two-component signal transduction pathways to sense and respond to environmental and intracellular stimuli. Upon receipt of a stimulus, a homodimeric sensor histidine kinase autophosphorylates and then transfers its phosphoryl group to a cognate response regulator. The autoph...

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Bibliographic Details
Main Authors: Ashenberg, Orr (Contributor), Keating, Amy E. (Contributor), Laub, Michael T (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Laub, Michael T. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-02-25T02:58:29Z.
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