Alzheimer's loci: epigenetic associations and interaction with genetic factors

Alzheimer's loci: epigenetic associations and interaction with genetic factors

Objective We explore the role of DNA methylation in Alzheimer's disease (AD). To elucidate where DNA methylation falls along the causal pathway linking risk factors to disease, we examine causal models to assess its role in the pathology of AD. Methods DNA methylation profiles were generated in...

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Bibliographic Details
Main Authors: Chibnik, Lori B. (Author), Yu, Lei (Author), Srivastava, Gyan (Author), Schneider, Julie A. (Author), Kellis, Manolis (Contributor), Bennett, David A. (Author), De Jager, Philip L. (Author), Eaton, Matthew Lucas (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: American Neurological Association, 2016-01-10T21:21:48Z.
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