Antimicrobial and anti-inflammatory activities of Piper porphyrophyllum (Fam. Piperaceae)

The crude extracts and isolated compounds of Piper porphyrophyllum (Piperaceae) were evaluated for antibacterial and anti-inflammatory activities. The ethyl acetate extract and 3',4',5,7-tetramethoxyflavone exhibited the highest activity against Staphylococcus aureus giving values of MIC =...

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Bibliographic Details
Main Authors: Ahmad, Farediah (Author), Emrizal, Emrizal (Author), M.Sirat, Hasnah (Author), Jamaludin, Fadzureena (Author), Mustapha, Nik Musa'adah (Author), M.Ali, Rasadah (Author), Arbain, Dayar (Author), Aboul-Enein, Hassan Y. (Author)
Format: Article
Language:English
Published: Elsevier B.V., 2014.
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Online Access:Get fulltext
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042 |a dc 
100 1 0 |a Ahmad, Farediah  |e author 
700 1 0 |a Emrizal, Emrizal  |e author 
700 1 0 |a M.Sirat, Hasnah  |e author 
700 1 0 |a Jamaludin, Fadzureena  |e author 
700 1 0 |a Mustapha, Nik Musa'adah  |e author 
700 1 0 |a M.Ali, Rasadah  |e author 
700 1 0 |a Arbain, Dayar  |e author 
700 1 0 |a Aboul-Enein, Hassan Y.  |e author 
245 0 0 |a Antimicrobial and anti-inflammatory activities of Piper porphyrophyllum (Fam. Piperaceae) 
260 |b Elsevier B.V.,   |c 2014. 
856 |z Get fulltext  |u http://eprints.utm.my/id/eprint/51873/1/FarediahAhmad2014_AntimicrobialAndAnti-inflammatory.pdf 
520 |a The crude extracts and isolated compounds of Piper porphyrophyllum (Piperaceae) were evaluated for antibacterial and anti-inflammatory activities. The ethyl acetate extract and 3',4',5,7-tetramethoxyflavone exhibited the highest activity against Staphylococcus aureus giving values of MIC = 62.5 and 250 μg/mL, respectively. 5-Hydroxy-7-methoxyflavanone and 4',5-dihydroxy-3',7-dimethoxyflavone were active against Pseudomonas aeruginosa, both with MIC value 125 μg/mL. The hexane extract and 4',5-dihydroxy-3',7-dimethoxyflavone gave the highest anti-inflammatory activity in in vitro quantitative lipoxygenase inhibition assay with inhibitory activity of (IE) 99.72% and 91.81%, respectively. 
546 |a en 
650 0 4 |a Q Science