Simultaneous non-negative matrix factorization for multiple large scale gene expression datasets in toxicology.

Non-negative matrix factorization is a useful tool for reducing the dimension of large datasets. This work considers simultaneous non-negative matrix factorization of multiple sources of data. In particular, we perform the first study that involves more than two datasets. We discuss the algorithmic...

Full description

Bibliographic Details
Main Authors: Clare M Lee, Manikhandan A V Mudaliar, D R Haggart, C Roland Wolf, Gino Miele, J Keith Vass, Desmond J Higham, Daniel Crowther
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3522745?pdf=render