Lin28a protects against hypoxia/reoxygenation induced cardiomyocytes apoptosis by alleviating mitochondrial dysfunction under high glucose/high fat conditions.

Lin28a protects against hypoxia/reoxygenation induced cardiomyocytes apoptosis by alleviating mitochondrial dysfunction under high glucose/high fat conditions.

The aim of the present study was to investigate the role of Lin28a in protecting against hypoxia/reoxygenation (H/R)-induced cardiomyocytes apoptosis under high glucose/high fat (HG/HF) conditions.Primary cardiomyocytes which were isolated from neonatal mouse were randomized to be treated with lenti...

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Bibliographic Details
Main Authors: Mingming Zhang, Xiaolin Niu, Jianqiang Hu, Yuan Yuan, Shuhong Sun, Jiaxing Wang, Wenjun Yu, Chen Wang, Dongdong Sun, Haichang Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4196990?pdf=render

Internet

http://europepmc.org/articles/PMC4196990?pdf=render

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