Keratinocyte sheets prepared with temperature-responsive dishes show enhanced survival after in vivo grafting on acellular dermal matrices in a rat model of staged bi-layered skin reconstruction

Introduction: Bi-layered skin reconstruction can be achieved by staged grafting of acellular dermal matrices (ADMs) and cultured epithelial keratinocyte sheets (KSs). Both KSs and ADMs have been used for long; yet, their combined use has shown poor effectiveness. This outcome has been related to the...

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Bibliographic Details
Main Authors: Hajime Matsumine, Giorgio Giatsidis, Atsuyoshi Osada, Wataru Kamei, Hiroshi Fujimaki, Yasuhiro Tsukamoto, Kazuki Hashimoto, Kaori Fujii, Hiroyuki Sakurai
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Regenerative Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320419300689