Protective role of FKBP51 in calcium entry-induced endothelial barrier disruption
Pulmonary artery endothelial cells (PAECs) express a cation current, I SOC (store-operated calcium entry current), which when activated permits calcium entry leading to inter-endothelial cell gap formation. The large molecular weight immunophilin FKBP51 inhibits I SOC but not other calcium entry pat...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2018-01-01
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Series: | Pulmonary Circulation |
Online Access: | https://doi.org/10.1177/2045893217749987 |