CRISPR-Cas9 Mediated Labelling Allows for Single Molecule Imaging and Resolution

Abstract Single molecule imaging approaches like dSTORM and PALM resolve structures at 10–20 nm, and allow for unique insights into protein stoichiometry and spatial relationships. However, key obstacles remain in developing highly accurate quantitative single molecule approaches. The genomic taggin...

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Bibliographic Details
Main Authors: Abdullah O. Khan, Victoria A. Simms, Jeremy A. Pike, Steven G. Thomas, Neil V. Morgan
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08493-x