A Prospective, Randomized, Placebo-Controlled Study of a Combination of Simvastatin and Chemotherapy in Metastatic Breast Cancer

Preclinical studies support the anticancer activity of statins; however, the existing clinical evidence is inconsistent and not definitive. Our study aimed at evaluating a postulated cancer chemo-sensitizing effect of statin (simvastatin) in a cohort of metastatic breast cancer (MBC) patients. We de...

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Bibliographic Details
Main Authors: Hiba Alarfi, Lama A. Youssef, Maher Salamoon
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2020/4174395