BP1 Homeoprotein Enhances Metastatic Potential in Er-Negative Breast Cancer

<p>Tumor invasion and metastasis remain a major cause of mortality in breast cancer patients. It was reported that BP1, a homeobox isoform of DLX4, is overexpressed in 80% of breast cancer patients and in 100% of estrogen receptor negative (ER-) tumors. The prevalence of BP1 positive cells and...

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Bibliographic Details
Main Author: Yebo Fu, Yi Lian, Kyung Soon Kim, Lei Zhang, A. Katharine Hindle, Fred Brody, Robert S. Siegel, Timothy A. McCaffrey, Sidney W. Fu
Format: Article
Language:English
Published: Ivyspring International Publisher 2010-01-01
Series:Journal of Cancer
Online Access:http://www.jcancer.org/v01p0054.htm