Identification of the Acinetobacter baumannii Ribonuclease P Catalytic Subunit: Cleavage of a Target mRNA in the Presence of an External Guide Sequence

Identification of the Acinetobacter baumannii Ribonuclease P Catalytic Subunit: Cleavage of a Target mRNA in the Presence of an External Guide Sequence

The bacterial ribonuclease P or RNase P holoenzyme is usually composed of a catalytic RNA subunit, M1, and a cofactor protein, C5. This enzyme was first identified for its role in maturation of tRNAs by endonucleolytic cleavage of the pre-tRNA. The RNase P endonucleolytic activity is characterized b...

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Bibliographic Details
Main Authors: Carol Davies-Sala, Saumya Jani, Angeles Zorreguieta, Marcelo E. Tolmasky
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Microbiology
Subjects:
RNase P
Acinetobacter
ESKAPE
ribozyme
EGS technology
antisense
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02408/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02408/full

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